Effects of gasoline exposure on some haematological and coagulation parameters among fuel attendants in Sokoto metropolis
DOI:
https://doi.org/10.53704/Keywords:
Petrol station workers, gasoline, haematological and coagulation parameterAbstract
Gasoline is always available in the atmosphere whenever it is distributed, particularly at gas stations and depots. Excessive benzene exposure has been shown to affect bone marrow, leading to a reduction in circulating blood cells. This cross-sectional study aimed at determining the effects of petroleum on haematological and coagulation parameters among occupational workers. A total of 80 participants were recruited, 40 exposed (5 females, 35 males) and 40 controls (20 females, 20 males). A simple random sampling method was used, and a questionnaire was administered. Socio-demographic data of the study participants were taken. A full blood count was performed using a haematological analyser. Coagulation parameters were measured using the manual method at 37 °C. The results showed a statistically significant increase in the exposed group compared to the control group in Red Blood Cells (RBC) (5.77±0.78; 5.77±0.78), Haemoglobin (Hb) (13.27±1.48; 11.81±1.56), and Haematocrit (HCT) (41.89±5.19; 38.02±4.13), p<0.001, respectively. The Partial Thrombin Time and Kaolin (PTTK) results showed a statistically significant increase in the exposed compared to the control group (41.13±8.37; 30.28±5.61), p<0.001. The Prothrombin Time (PT) (13.03±0.28; 14.25±1.32) and International Normalised Ratio (INR) (1.002±0.02; 1.096±0.09) p<0.001 were statistically decreased between the exposed and the control group, respectively. There was a statistically significant negative correlation between PT, RBC (r= -0.295), PT, HCT (r= -0.310), and between INR, RBC (r= -0.301), INR, HCT (r= -0.315), p<0.05, respectively. This research showed a significant effect on the coagulation parameters. Hence, protective equipment for petrol station workers should be used to minimise exposure to gasoline.
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